thedynamictrend.com

Wednesday, December 7, 2005

Australian researchers say they have scientifically proven that stress causes sickness. The Garvan Institute in Sydney has discovered that a hormone, known as neuropeptide Y (NPY) is released into the body during times of stress. Their findings show the hormone can stop the immune system from functioning properly.

“Neuropeptide Y is one of those hormones that gets unregulated or released from neurones when stressful situations occur…it’s known for example that it regulates blood pressure and heart rates so your heart rate goes up but it hasn’t been known that it actually can affect immune cells as well,” said Professor Herbert Herzog, one of the researchers.

Herzog feels it is good to finally have proof of something people have suspected for so long.

“Now we have proven without doubt that there is a direct link and that stress can weaken the immune system and that makes you more vulnerable when you for example have a cold or flu and even in the more serious situations such as cancer can be enhanced in these situations,” said Herzog.

The Garvan Institute study centres on two key events that enable the human body to recognise foreign substances and control invaders. When our body encounters a pathogen (bacteria and viruses), the immune cells retain and interrogate suspects. Their activation is made possible by NPY. These cells then return to the lymph nodes, which are found all over the body, with information about the foreign invaders. The lymph nodes are where decisions about defence are made.

“Most of us expect to come down with a cold or other illness when we are under pressure, but until now we have mostly had circumstantial evidence for a link between the brain and the immune system,” said lead Garvan researcher, associate Professor Fabienne Mackay. “During periods of stress, nerves release a lot of NPY and it gets into the bloodstream, where it directly impacts on the cells in the immune system that look out for and destroy pathogens (bacteria and viruses) in the body.”

In the case of bacteria and viruses, TH1 cells are part of the attack team that is sent out on the ‘search and destroy’ mission. But when their job is done they need to be turned ‘off’ and the immune system reset. The same hormone, NPY, that activates the sentry cells now prompts the TH1 cells to slow down and die.

“Under normal conditions, circulating immune cells produce small amounts of NPY, which enables the immune cells on sentry duty and the TH1 immune cells to operate – it’s a yin and yang kind of situation. But too much NPY means that the TH1 attack is prevented despite the foreign invaders being identified – and this is what happens during stress,” added McKay.

The impact of stress on the body has been observed in athletes. Ph. D researcher at the University of Queensland, Luke Spence, together with the Australian Institute of Sport, studied elite and recreational athletes over five months.

They found elite athletes were more susceptible to respiratory diseases under stress.

“A lot of elite athletes put themselves through vast amounts of physical stress in their training, but also their emotional, psychological stress of feeling the pressure of Australia on their shoulders, wanting to compete and wanting to do their best,” said Spence.

It’s not just athletes who are prone to stress. Pressures at work and at home may cause emotional and mental stress that can be equally damaging. Almost a third of all work absenteeism in Australia is due to illness, costing employers over $10 billion a year.

“I think it has a huge impact for the work force and also for employers – if their employees are constantly stressed, constantly under pressure, they are more likely to get sick,” Spence said.

Further research could lead to the development of new drugs which may inhibit the action of the neuropeptide Y hormone.

Herzog warns people to minimise stress before it becomes a problem.

“Relaxation methods like yoga will help you to prevent that but there will still be people out there that are not responding to that and treatment by interfering with the system will be important,” he said. “There’s obviously some time until such a treatment will be available but this is something we will definitely work towards.”

The Garvan research will be published in the Journal of Experimental Medicine, Volume 202, No. 11.

Tuesday, March 25, 2014

Dave Brockie of rubber-costumed metal act GWAR was found dead in his Richmond, Virginia home late on Sunday. Better known by stage name Oderus Urungus, Brockie was 50.

Founder, singer, leader, and occasional bassist of GWAR, Brockie’s career stretches back to 1984. He and fellow Virginia Commonwealth University art students formed what they dubbed “Earth’s only openly extra-terrestrial rock band”, growing famous for satirical and obscene lyrical themes, and live shows featuring the defilement of effigies and plenty of fake blood.

Fellow founding member Don Drakulich, who still makes props and costumes for the rockers, said he was “very sad” and “shocked”. He said Brockie’s roommate found the corpse. GWAR members changed frequently and the band recovered from the sudden death of guitarist Cory “Flattus Maximus” Smoot during a 2011 tour, but the New York Daily News notes “it’s hard to envision their saga going further” after Brockie’s death.

The band ran with the backstory of crashing to “the most insignificant planet in the universe” 43 million years ago before creating humans by having sex with apes. Becoming encased with ice, the legend ran that upon thawing out in 1984 the members decided to form a band.

Manager Jack Flanagan announced the death via GWAR’s website, adding a post-mortem will be conducted. “My main focus right now is to look after my band mates and his family” he said. Flanagan said another GWAR member found the body.

Brockie said in 2009 “I am one of the blessed people that gets to do what I love to do for a living.” GWAR received a Grammy nomination in 1993, with Phallus in Wonderland up for Best Longform Music Video.

Fellow Virginia rocker Randy Blythe, vocalist for Lamb of God, paid tribute online, writing on Instagram “When someone dies, a lot of the time people will say ‘Oh, he was a unique person, really one of a kind, a true original’ […] I can’t think of ANYONE even remotely like him.”

Blythe also took to Facebook. “Right now, if I were to truly honor Dave in the way HE would do it if it were ME that had died, I would make a completely tasteless joke about his death. But I do not have the stomach for that — Dave would, but not me. He never put much stock in ‘limits’.”

Ex-GWAR guitarist Steve Douglas said on Facebook “I have had a few bad days in my life but this one truly ranks right up there. […] you are gone and it is hurting very badly!” “I wish it was a joke” said another ex-member, Chris Bopst. “Everyone is in shock.”

Former bassist Mike Bishop paid tribute in an interview with Style Weekly. “Dave was one of the funniest, smartest, most creative and energetic persons I’ve known,” he said. “He was brash sometimes, always crass, irreverent, he was hilarious in every way. But he was also deeply intelligent and interested in life, history, politics and art.”

Thursday, March 8, 2007

Computer systems used by the Canada Revenue Agency (CRA) for the handling of tax filing data for Canadians have been temporarily shutdown due to infrastructure problems.^[1] A March 7 article in the Toronto Star^[2] states that due to errors in the electronic filing system, Canada Revenue Agency will be unable to accept any tax filings electronically or corrections to prior filings.

A fact sheet from the CRA ^[3] states that “until the problem is resolved, we cannot process returns filed on paper, or returns filed electronically before the system interruption. Refunds will be delayed until processing is resumed”.

A check of the taxing authority’s website^[4] regarding the issue states “We have temporarily shut down public access to electronic services to ensure the integrity of taxpayer information.” and that “We have now traced the source of the problem to software maintenance conducted on March 4, 2007. We are currently working to bring all systems back online gradually.”

A CRA press release dated March 6 ^[5] states “Commissioner of the Canada Revenue Agency (CRA) Michel Dorais today instructed some computer applications related to personal income tax filing to be temporarily halted.” he also said, “there is no indication that this situation was caused by intrusion, hacking, or computer virus”. Further, “These applications include online services like Efile, Netfile, and My Account. Mr. Dorais said that he instructed that this preventative measure be taken following indications that CRA computer systems have run into infrastructure problems. In order to safeguard existing systems and to maintain the integrity of CRA’s taxpayer information holdings, Mr Dorais ordered tax filing processes halted.”

An article in The Globe and Mail ^[6] states that taxpayers “can wait for Netfile to return to service, or they can print their returns and mail them to the CRA”, which will be processed when the computer glitch is resolved.

The deadline for Canadians to submit tax returns is April 30. The CRA indicates it is too soon to speculate on whether the filing deadline will be extended. They expect to restore all services, including EFile and Netfile, well in advance of the filing deadline.^[7]

The shutdown also affects third-party companies that prepare tax returns and electronically file the data using the EFile facility on behalf of clients. According to the CRA, millions of individual Canadians use the Netfile service each year.

The Agency will provide updates daily to the media until the situation is resolved.

Friday, November 30, 2007

Christine Comer resigned this month as the director of the science curriculum for the Texas Education Agency‘s (TEA) director after more than nine years. Comer said her resignation was due to pressure from officials who claimed she had given the appearance of criticizing the teaching of intelligent design.

According to documents obtained by the Austin American-Statesman, “Comer was put on 30 days paid administrative leave shortly after she forwarded an e-mail in late October announcing a presentation by Barbara Forrest, a critic of the intelligent design/creationist movement. Forrest served as an expert witness at the Kitzmiller v. Dover Area School District trial. At Dover, intelligent design was ruled “a religious view, a mere re-labeling of creationism, and not a scientific theory.” There is widespread scientific support for evolution, while creationism has been described as pseudoscience by the scientific community.

Comer’s resignation comes shortly ahead of the TEA’s State Board of Education (SBOE) reviews of the Texas Essential Knowledge and Skills (TEKS), which determine what should be taught in the classrooms and what textbooks are bought.

The advocacy group Texas Citizens for Science have released a statement saying, in part, “The real reason [Comer] was forced to resign is because the top TEA administrators and some SBOE members wanted her out of the picture before the state science standards—the science TEKS—were reviewed, revised, and rewritten next year. Plans are underway by some SBOE members and TEA administrators to diminish the requirement to teach about evolutionary biology in the Biology TEKS and to require instead that biology instructors ‘Teach the Controversy’ about the ‘weaknesses’ of evolution, that is, teach the Creationist-inspired and -created bogus controversy about evolution that doesn’t exist within legitimate science.”

Professor PZ Myers, biology professor at the University of Minnesota, Morris, wrote that Forrest is “exactly the kind of person boards of education ought to consult before going down the road of attempting to legislate religion into the public schools.”

In reaction to the news Forrest told National Center for Science Education, “In my talk, I simply told the truth — about the history of the ‘intelligent design’ movement, about the complete rejection of its claims by the scientific community, and about the Kitzmiller trial and my involvement in it. Maybe the TEA can’t afford to take a position on what constitutes good science education — maybe it must remain neutral on whether or not to lie to students about evolution — but if so, that’s just sad.”

Agency officials declined to comment, saying it was a personnel issue.

Friday, April 13, 2007

Google has announced its intention of taking over the Internet advertising agency DoubleClick in a deal worth $3.1 billion. DoubleClick has also confirmed the deal and hopes it will be completed before the end of 2007.

Rumours of a takeover offer for DoubleClick had been circulating, with Microsoft, Time Warner and Yahoo! all reportedly interested in making an offer for the company.

Six months ago, Google bought YouTube for $1.65 billion. The current takeover is the largest in Google’s history. In a press release, Google says the acquisition “will enable Google to extend our ad network and develop deeper relationships with our partners. This new partnership represents a tremendous opportunity for us at Google to broaden and deepen our inventory of available ads and to better serve both our publishers and users.”

DoubleClick provides software for Internet advertising and brings together advertisers, advertisement agencies and website developers. DoubleClick is currently owned by the majority share-holders Hellman & Friedman, a private equity firm, with JMI Management also having a large stake in the company.

Friday, June 3, 2011

Although prom may have taken place over two weeks ago at Maine’s Sanford High School, the fact that students elected a gay couple as prom king and queen remains the talk of the local community.

During the May 14 event, 17-year-old Christian Nelsen was named prom queen, running as a write-in candidate. One of Nelsen’s friends, Holly Smith, spoke of the help they provided in getting him elected: “The day of prom, we went downstairs, and he was yelling ‘Vote for Christian Nelsen!’ And I was helping people spell his name, or telling them how to write it on the ballot”.

Nelsen’s boyfriend, Caleb Jett, was elected prom king. “I kinda got voted in because he got queen, and it was like ‘Who do we vote for king?’ and it was like ‘Oh, well, his boyfriend, obviously, because that makes sense,'” he said. The two young men wore suits, shirts, and ties to the prom. When the results of the election were announced, they danced the king-queen dance together, Jett wearing his crown and Nelsen his tiara.

Maine is one of only two states in New England that have not recognized same-sex marriages. Though they are aware that not everyone supports them, the couple ran to combat high school stereotypes and to encourage more tolerance. Nelsen commented, “It doesn’t matter if it’s a guy or a girl who wins prom king or prom queen from now on. Anyone can win, and on that same notion any type of person can win. And I’m talking about the tolerance level of all people when I talk about that, so anyone who is bullied or even just under the radar can win this type of thing.”

Minister of a parish of the United Church of Christ Reverend Diane Wendorf supported the couple, citing her church’s values of tolerance and diversity. “I’m glad, too, that they were crowned king and queen, because there are all different kinds of people in this world.” Some Sanford residents a local news agency interviewed did not approve of the gay couple’s crowning, though none agreed to go on camera — out of concerns that their comments might offend someone.

The matter is expected to be brought up by interested citizens at an upcoming school committee meeting. Committee Chair Mark Lucier stated that the school is gathering information on the election, and that the committee may decide if it needs to address the future selection of prom kings and queens.